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Table 1 Stages of exploratory and explanatory analysis shared across scientists

From: Supporting cognition in systems biology analysis: findings on users' processes and design implications

Stage (its dominant reasoning) % completing this stage Description
Confirmation (validation) 100% Scientists vetted query results and the tool for accuracy, reliability, and timeliness Example: Look for familiar literature references.
Separating Wheat From Chaff (classification and validation) 85% Scientists classified relationships to find genes and protein interactions of interest Example: Locate an interaction between a candidate gene from experimental findings and a gene product known to be associated with a disease
Beyond Read-offs (Model-based reasoning and validation) 0 Scientists wanted to place relationships of interest in local and global contexts to mentally model explanatory biological events relevant to a disease. Example: Contextualize significant regulatory relationships in pathways.
Story-building (narrative reasoning and validation) 0 Scientists sought to turn explanations about biological events into new, credible and plausible biological stories. Examples considered to be credible were not available based on scientists' progress.