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Table 3 Federal Funding to Affymetrix (1993–2003)

From: The emergence and diffusion of DNA microarray technology

Award Number

AvgAnnual (in $K)

Start

End

Total (in $K)

Government Entity

SBIR

Brief Description

FG0392ER81275

137.5

Jul-92

May-95

550.0

Basic energy sciences (Dept. of Energy)

Y

SBIR phase I: develop spatially defined oligonucleotide arrays

R01HG000813

465.8

Sep-93

Aug-95

NA

National Human Genome Research Institute

N

The long term goals of this proposal are to construct spatially defined arrays of oligonucleotide probes and to study the feasibility of using these arrays in applications of sequencing DNA by hybridization. A multidisciplinary research program is proposed which will integrate the necessary expertise in photolithography, photochemistry, synthetic chemistry, detection technology, informatics and applications to large scale DNA sequencing.

F32HG000105

20.3

Jun-93

Aug-96

NA

National Human Genome Research Institute

N

NA

R43AI036809

37.5

Jul-94

Jan-95

75.0

National Institute of Allergy and Infectious Diseases

Y

Rapid detection of HIV drug resistance

70NANB5H1031

5,246.3

Feb-95

Jan-00

31,478

Advanced Technology Program

N

Capillary-array electrophoresis, which separates and sizes DNA fragments, for use in a compact, reusable system for use with patient blood samples in labs and hospitals. Lawrence Livermore National Laboratory, Stanford University, the University of California (Berkeley), the California Institute of Technology, and the University of Washington also will work on the project.

R43CA067604

100.0

Mar-95

Sep-95

100.0

National Cancer Institute

Y

Detection of mutations in human p53, msh2, mlh1 genes

R43DA010389

50.0

Sep-95

Mar-96

100.0

National Institute on Drug Abuse

Y

Typing human cytochrome p450 genes using DNA chips

A64472D

27.6

Jul-01

Jul-01

27.6

Human health and performance (NASA)

N

Studying the rat genome

P01HG001323

1,377.5

Sep-95

Aug-98

NA

National Human Genome Research Institute

N

Human genome sequencing and mapping with dna probe arrays

R41CA075675

49.8

Jul-97

Sep-98

99.7

National Cancer Institute

N

Genotype for radiation sensitivity in cancer patients

R43AI040400

50.0

Sep-96

Mar-97

100.0

National Institute of Allergy and Infectious Diseases

Y

Chip based genotyping of mycobacterium drug resistance

R43CA081949

133.3

Jul-99

Sep-99

133.3

National Cancer Institute

Y

Reverese engineering biological signal transduction networks

R43HD038622

50.0

Sep-00

Aug-01

100.0

National Institute of Child Health and Human Development

Y

Gene expression in endometriosis

R43HG001481

33.3

Apr-96

Oct-97

33.3

National Human Genome Research Institute

Y

Mutation screening of the human mitochondrial genome

R43NS036491

50.0

Jul-97

Jan-98

100.0

National Institute of Neurological Disorders and Stroke

Y

Cytokine message monitoring in oral tolerance

R44AI036809

250.0

Aug-95

Jul-97

372.6

National Institute of Allergy and Infectious Diseases

Y

Rapid detection of HIV 1 drug resistance

R44CA067604

244.3

Mar-96

Feb-98

359.3

National Cancer Institute

Y

Phase II of earlier project to develop a rapid and efficient method for detecting mutations on the human p53, msh2 and mlh1 genes

R44DA010389

163.9

Sep-96

Aug-98

205.5

National Institute on Drug Abuse

Y

Phase II of earlier project for typing human cytochrome p450 genes using DNA chips

R44DK053325

237.7

Jul-97

Sep-99

86.7

National Institute of Diabetes and Digestive and Kidney Diseases

Y

Genomic responses to hormone signaling

R44HG001481

249.2

Jul-97

Aug-99

368.5

National Human Genome Research Institute

Y

Continuation of mutation screening of the human mitochondrial genome project

U01HG003147

661.0

Sep-03

Jul-05

985.5*

National Human Genome Research Institute

N

Mapping sites of transcription and regulation