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  1. Research

    Basic Blue Skies Research in the UK: Are we losing out?

    The term blue skies research implies a freedom to carry out flexible, curiosity-driven research that leads to outcomes not envisaged at the outset. This research often challenges accepted thinking and introduc...

    Belinda Linden

    Journal of Biomedical Discovery and Collaboration 2008 3:3

    Published on: 29 February 2008

  2. Research

    Corpus Refactoring: a Feasibility Study

    Most biomedical corpora have not been used outside of the lab that created them, despite the fact that the availability of the gold-standard evaluation data that they provide is one of the rate-limiting factor...

    Helen L Johnson, William A Baumgartner, Martin Krallinger, K Bretonnel Cohen and Lawrence Hunter

    Journal of Biomedical Discovery and Collaboration 2007 2:4

    Published on: 13 September 2007

  3. Research

    Applied information retrieval and multidisciplinary research: new mechanistic hypotheses in Complex Regional Pain Syndrome

    Collaborative efforts of physicians and basic scientists are often necessary in the investigation of complex disorders. Difficulties can arise, however, when large amounts of information need to reviewed. Adva...

    Kristina M Hettne, Marissa de Mos, Anke GJ de Bruijn, Marc Weeber, Scott Boyer, Erik M van Mulligen, Montserrat Cases, Jordi Mestres and Johan van der Lei

    Journal of Biomedical Discovery and Collaboration 2007 2:2

    Published on: 4 May 2007

  4. Focus

    Biological information specialists for biological informatics

    Data management and integration are complicated and ongoing problems that will require commitment of resources and expertise from the various biological science communities. Primary components of successful cr...

    P Bryan Heidorn, Carole L Palmer and Dan Wright

    Journal of Biomedical Discovery and Collaboration 2007 2:1

    Published on: 12 February 2007

  5. Software

    GOAnnotator: linking protein GO annotations to evidence text

    Annotation of proteins with gene ontology (GO) terms is ongoing work and a complex task. Manual GO annotation is precise and precious, but it is time-consuming. Therefore, instead of curated annotations most o...

    Francisco M Couto, Mário J Silva, Vivian Lee, Emily Dimmer, Evelyn Camon, Rolf Apweiler, Harald Kirsch and Dietrich Rebholz-Schuhmann

    Journal of Biomedical Discovery and Collaboration 2006 1:19

    Published on: 20 December 2006

  6. Focus

    What makes humanity humane

    Scientific and popular lore have promulgated a connection between emotion and the limbic forebrain. However, there are a variety of structures that are considered limbic, and disagreement as to what is meant b...

    Karl H Pribram

    Journal of Biomedical Discovery and Collaboration 2006 1:14

    Published on: 29 November 2006

  7. Focus

    Karl Pribram, the James Arthur Lectures, and What Makes Us Human

    The annual James Arthur lecture series on the Evolution of the Human Brain was inaugurated at the American Museum of Natural History in 1932, through a bequest from a successful manufacturer with a particular ...

    Ian Tattersall

    Journal of Biomedical Discovery and Collaboration 2006 1:15

    Published on: 29 November 2006

  8. Focus

    Who's afraid of Homo sapiens?

    Understanding how humans differ from other animals, as well as how we are like them, requires comparative investigations. For the purpose of documenting the distinctive features of humans, the most informative...

    Todd M Preuss

    Journal of Biomedical Discovery and Collaboration 2006 1:17

    Published on: 29 November 2006

  9. Review

    What makes us human: revisiting an age-old question in the genomic era

    In 1970, Karl Pribram took on the immense challenge of asking the question, what makes us human? Nearly four decades later, the most significant finding has been the undeniable realization of how incredibly su...

    Nitzan Mekel-Bobrov and Bruce T Lahn

    Journal of Biomedical Discovery and Collaboration 2006 1:18

    Published on: 29 November 2006

  10. Editorial

    Introduction to a special series: What Makes Man Human

    One of the most pressing and timely scientific questions concerns the evolution of man. In 1970, Karl Pribram delivered the James Arthur Lecture at the American Museum of Natural History in New York City. His ...

    Neil R Smalheiser

    Journal of Biomedical Discovery and Collaboration 2006 1:12

    Published on: 28 November 2006

  11. Case Study

    The emergence and diffusion of DNA microarray technology

    The network model of innovation widely adopted among researchers in the economics of science and technology posits relatively porous boundaries between firms and academic research programs and a bi-directional...

    Tim Lenoir and Eric Giannella

    Journal of Biomedical Discovery and Collaboration 2006 1:11

    Published on: 22 August 2006

  12. Research

    Collaborative development of the Arrowsmith two node search interface designed for laboratory investigators

    Arrowsmith is a unique computer-assisted strategy designed to assist investigators in detecting biologically-relevant connections between two disparate sets of articles in Medline. This paper describes how an ...

    Neil R Smalheiser, Vetle I Torvik, Amanda Bischoff-Grethe, Lauren B Burhans, Michael Gabriel, Ramin Homayouni, Alireza Kashef, Maryann E Martone, Guy A Perkins, Diana L Price, Andrew C Talk and Ruth West

    Journal of Biomedical Discovery and Collaboration 2006 1:8

    Published on: 3 July 2006

  13. Case Study

    The effects of business practices, licensing, and intellectual property on development and dissemination of the polymerase chain reaction: case study

    Polymerase chain reaction (PCR) was a seminal genomic technology discovered, developed, and patented in an industry setting. Since the first of its core patents expired in March, 2005, we are in a position to ...

    Joe Fore, Ilse R Wiechers and Robert Cook-Deegan

    Journal of Biomedical Discovery and Collaboration 2006 1:7

    Published on: 3 July 2006

  14. Focus

    Nomen est Omen: do antidepressants increase p11 or S100A10?

    Occasionally, multiple names are given to the same gene/protein. When this happens, different names can be used in subsequent publications, for example in different research areas, sometimes with little or no ...

    Hari Manev and Radmila Manev

    Journal of Biomedical Discovery and Collaboration 2006 1:5

    Published on: 13 April 2006

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